Amorphous solid dispersions of ritonavir by melt-quenching

Properties using metallic amorphous ribbons from (Fe-Co-Ni)- metalloid system, obtained by melt-quenching

Characterization of Olanzapine – Solid dispersions.

Aim: To enhance the aqueous solubility of olanzapine by using the Solid dispersion technique. Solid dispersions of Olanzapine were prepared by the dispersion method using using PGS and SSG as carriers. Drug:carrier ratios such as 1:1, 1:2, 1:4, 1:6, 1:8 and 1:10 were tried for optimization. Characterization was done by phase solubility, in vitro release, saturation solubility, permeation, wetta...

Fabrication and Structural Characterization of Se-Ge Chalcogenide Glasses by Means of Melt Quenching Technique

The structural and optical characterization of Se-Ge alloys during melt quenching technique was the goal of this study. In this regards, five different samples of Se100-xGex (x= 10, 20, 30, 40, 50) were prepared by conventional melt quenching in quartz ampoule. The produced samples were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), differential scanning calori...

Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions.

In this study, amorphous solid dispersions containing dutasteride and various excipients, manufactured by spray-drying processes, were characterized to determine the effects on their ability to form supersaturated solutions and to identify the effects of supersaturation on increasing the bioavailability of dutasteride. The excipients included Eudragit E, hydroxypropyl-β-cyclodextrin (HP-β-CD), ...

Characterization of Olanzapine – Solid dispersions.

Aim: To enhance the aqueous solubility of olanzapine by using the Solid dispersion technique. Solid dispersions of Olanzapine were prepared by the dispersion method using using PGS and SSG as carriers. Drug:carrier ratios such as 1:1, 1:2, 1:4, 1:6, 1:8 and 1:10 were tried for optimization. Characterization was done by phase solubility, in vitro release, saturation solubility, permeation, wetta...